Community health centers are a national network of over 1,300 safety-net primary care providers, serving more than 30 million patients in 2022. They are located in medically underserved urban and rural communities and serve all patients regardless of their ability to pay. Health centers also played a major role in the nation’s response to the coronavirus pandemic, particularly for hard-to-reach populations. This brief analyzes the changes in health center patients, services, and financing from 2019 (pre-pandemic) through 2022, using the Uniform Data System (UDS), to which all health centers are required to report annually.